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Thorne Complete Biotic — 360° Intestinal Support
3-in-1 Formula · Clinically Studied

Complete
Biotic

The only formula that combines prebiotics, probiotics, and postbiotics in a fast-dissolving sachet — 360° support for your gut and immune health.

Balanced Microbiome Digestive Health No Swelling
Buy — 30 Sachets
Thorne Complete Biotic
1 Billion CFUs per dose
+6× Lactobacillus colonization
4 years and older For the whole family
3-in-1
Pre, Pro and Postbiotics
30
Sachets per package
6x
More colonization with PreforPro®
84
Clinical study days

Three pillars,
a unique synergy

01

Prebiotic

PreforPro®

Bacteriophage technology that eliminates pathogenic bacteria and prepares the ground for beneficial bacteria to flourish — increasing Lactobacillus colonization by 6x.

02

Probiotic

Bacillus subtilis DE111®

A spore-forming strain that survives stomach acid and germinates directly in the small intestine — ensuring that the benefits reach where they are needed.

03

Postbiotic

Bifidobacterium longum ES1

Heat-treated strain that delivers direct anti-inflammatory and metabolic benefits without the need to maintain live organisms — maximum stability.

Prebiotic · Pillar 1
PreforPro®
Bacteriophages that create a fertile environment for beneficial flora.
15mg
Probiotic · Pillar 2
DE111®
Acid-resistant spores — 1 billion active CFUs
1B
Postbiotic · Pillar 3
B. longum ES1
Term-treated agreement for direct benefits and superior stability.
25mg

Systemic impact
besides digestion

🌿

Gastrointestinal Comfort

Reduces gas, bloating, and indigestion. Clinically tested on adults and children with results in a few weeks.

🛡️

Gut Immunity

It maintains balanced levels of sIgA and reduces inflammatory cytokines, strengthening the intestinal immune barrier.

Bowel Regularity

Optimizes intestinal transit — providing support for both occasional diarrhea and colds.

🔬

Balance of the Flora

It favors butyrate-producing strains over pathogenic organisms — reshaping the microbiome.

Science you
You can trust

Each component of the formula has been individually studied and the results are clinically documented. Complete Biotic doesn't focus on a single strain—it delivers a clinically studied triad to transform the gut ecosystem.

Reducing vomiting in children
Placebo: 14 days → Probiotic: 2 days
-86%
Improves IBS-D symptoms.
Within 28 days of use (84 days of study)
28d
Reducing hard stools in children
15 days (placebo) vs. 0 days (probiotic)
100%
Synergistic effect of PREFORPRO® on colonization
Isolated Probiotic
1x
Probiotic + PreforPro®
6x
Total cholesterol reduction (DE111®)
Healthy adults after 4 weeks
↓ LDL
Improves anxiety (Inner-Brain Axis)
ES1 heat-treated — IBS-D 84-day study
↓ HAD

Clinical versatility for
different profiles

Adults with Discomfort

Ideal for those suffering from gas, bloating, indigestion, and Irritable Bowel Syndrome (IBS). The triad acts directly on the causes of gastrointestinal discomfort.

Gas · Bloating · IBS

Individuals with Irregularity

For those experiencing transitions between episodes of occasional diarrhea or a cold. DE111® and ES1 work together to normalize bowel movements.

Regularity · Traffic

Children (from 4 years old)

Especially for children in daycare and school. Immune support and stool consistency proven in an 8-week study with significant results.

Immunity · Growth

As simple as
open and consume

1

Open the sachet.

Each package contains 30 sachets of 1g — an exact daily dose, no measuring required.

2

Pour directly onto the tongue.

The Fast-Melt format dissolves instantly. No water needed — perfect for use anywhere.

3

Swallow normally

The mild flavor of iced orange makes the ritual enjoyable for the whole family, including children over 4 years old.

Use daily

For best results, use consistently. Clinical results observed after 2–4 weeks of regular use.

Supplement Facts
Serving size: 1 stick (1g) · 30 servings per package
Postbiotic ES1 B. longum CECT7347 — heat treated
25 mg
Prebiotic PreforPro® Bacteriophage mix — patented technology
15 mg
DE111® Probiotic Bacillus subtilis — live spores
1B CFUs
(3.3 mg)

Now available on our website.

30 sachets · Iced orange flavor · For the whole family