Pyridoxal 5 Phosphate 180 Caps Thorne Research
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Boost your metabolism, support your immunity, and balance your nervous system with active vitamin B6.
🛒 Add Pyridoxal-5-Phosphate to your cart and feel the difference in your daily well-being!
Suitable for:
✅ People with an increased need for active vitamin B6 (e.g., stress, use of certain medications, restrictive diets).
✅ Individuals who want support for energy metabolism, nerve function, and immunity.
✅ Anyone who has symptoms that may be related to B6 deficiency: fatigue, mood swings, or slow metabolism.
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Description
Pyridoxal-5-Phosphate – Thorne | Active Vitamin B6 for Metabolism, Immunity & Energy
This is a vitamin B6 supplement in its biologically active form (P5P), which does not require liver conversion to be utilized by the body. It can be beneficial for those who want to support energy production, normal nervous system function, hormonal balance, or protein metabolism in their daily lives.
Vitamin B6 is essential for the body to function well — from energy production to neurotransmitter synthesis, as well as hormonal regulation and protein metabolism. To be used by the body, common vitamin B6 (pyridoxine) must be converted into its active form, pyridoxal-5'-phosphate (P5P). Those with impaired liver function, genetic variants that hinder this conversion, or increased vitamin B6 needs may not be able to perform this transformation effectively. Thorne's Pyridoxal 5'-Phosphate provides 33.8 mg of P5P per capsule — the active form, ready for the body to use — in a gluten-free, soy-free, and dairy-free vegetable capsule. One to three capsules daily can easily be incorporated into any routine.
✅ May contribute to energy-yielding metabolism and the reduction of tiredness and fatigue.
✅ Supports normal nervous system function and psychological function.
✅ Participates in the regulation of hormonal activity.
✅ May support normal red blood cell formation and protein metabolism.
✅ Coenzymatic (active) form of B6 – better absorption and efficacy.
✅ Free from gluten, lactose, soy, and preservatives.
Pyridoxal 5'-Phosphate (P5P) is the active form of vitamin B6, ready for use by the body, with no need for liver conversion.
The only active ingredient in this supplement is vitamin B6 in the form of pyridoxal-5'-phosphate (P5P), providing 33.8 mg per capsule. P5P is the active coenzymatic form of vitamin B6 — the one the body uses directly, without the need for additional liver conversion. This makes it particularly relevant for people with reduced liver function, genetic variants affecting B vitamin metabolism (such as MTHFR gene variants), or anyone who simply wants to ensure a direct intake of the most usable form of this vitamin. Vitamin B6 is essential for over 100 enzymatic reactions in the body, including the synthesis of neurotransmitters like serotonin and dopamine, hemoglobin production, the formation of the myelin sheath that surrounds nerve cells, and homocysteine metabolism. The product is not yeast-derived.
The excipients are microcrystalline cellulose, hydroxypropyl methylcellulose capsule (vegetable cellulose), calcium laurate, and silicon dioxide — all of plant or mineral origin. It does not contain gluten, soy, dairy, eggs, tree nuts, or shellfish.
Important to note
- Vitamin B6 doses above 200 mg/day can inhibit breast milk production — do not exceed the recommended dosage during breastfeeding without medical advice.
- If pregnant, consult a healthcare professional before starting supplementation.
- No adverse interactions are known with the P5P form at usual doses — unlike what was observed with very high doses of pyridoxine (common form), for which reversible neuropathies have been described.
- This product is not yeast-derived — relevant for those with yeast sensitivity.
How to Use: 1 Capsule daily, or as medically prescribed.
Nutritional Information
Vitamin B 6 (with Pyridoxal 5'Phosphate), 33.8 mg / **
Ingredients:Pyridoxal-5-phosphate, microcrystalline cellulose (filler), hypromellose capsule (vegetable), calcium laurate (superplasticizer), silicon dioxide (release agent
Food Preferences
- Vegetariano
- Cetogénico
- Vegano
- Não tem glúten
- Sem lactose
- Sem soja
- Sem conservantes
Suitable for various diets
- Vegetariano
- Cetogénico
- Vegano
- Não tem glúten
- Sem lactose
- Sem soja
- Sem conservantes
- Vegetariano
- Cetogénico
- Vegano
- Não tem glúten
- Sem lactose
- Sem soja
- Sem conservantes
Suporte imunitário
FAQs
What is Thorne Pyridoxal 5'-Phosphate used for?
Pyridoxal 5'-Phosphate is a vitamin B6 supplement in its active form (P5P), which can contribute to energy production, normal nervous system function, hormonal balance, protein metabolism, and red blood cell formation. It is particularly relevant for those who have difficulty converting common pyridoxine into its active form.
Who can benefit from this supplement?
It may be useful for individuals with compromised liver function, genetic variants such as MTHFR affecting B-vitamin metabolism, women with premenstrual syndrome (PMS) symptoms, people with persistent fatigue, mood imbalances, or elevated homocysteine levels. Conditions such as peripheral neuropathy, premenstrual syndrome, anaemia, anxiety, and neurotransmitter imbalances can benefit from adequate B6 intake — always in addition to medical supervision.
Can it be combined with magnesium?
Yes. Vitamin B6 and magnesium are frequently used together, especially in the context of supporting women's well-being and mood regulation. The combination of these two nutrients can complement their effects as part of a wellness routine — consult a healthcare professional for personalized guidance.
Notices
* NRV (Nutrient Reference Value)
** VRN not established.
Food supplements are not a substitute for a varied and balanced diet or a healthy lifestyle. If you are pregnant or breastfeeding, please contact your doctor before taking the supplements. Not recommended in cases of hypersensitivity or allergy to any of the ingredients in the formulation or when interactions of another product with any of the constituents of the formulation are described. Keep out of the reach and sight of children. Store in a cool, dry place, protected from light.
The recommended daily dose should not be exceeded.
Notices
* NRV (Nutrient Reference Value)
** VRN not established.
Food supplements are not a substitute for a varied and balanced diet or a healthy lifestyle. If you are pregnant or breastfeeding, please contact your doctor before taking the supplements. Not recommended in cases of hypersensitivity or allergy to any of the ingredients in the formulation or when interactions of another product with any of the constituents of the formulation are described. Keep out of the reach and sight of children. Store in a cool, dry place, protected from light.
The recommended daily dose should not be exceeded.
