Stress B-Complex 60 Caps Thorne Research
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✅ Those experiencing physical or mental fatigue.
✅ People with high daily demands, whether due to work, training, or stress.
✅ Those who want support for normal energy metabolism and to promote mental health & balanced mood.

Stress B‑Complex – Thorne | B Vitamin Support for Energy, Mood & Stress Response
Thorne Research's Stress B-Complex is a supplement that combines all essential B vitamins in highly bioavailable forms, ensuring maximum concentration and effectiveness. This product is specially formulated with a focus on pantothenic acid (vitamin B5), known for its vital role in energy metabolism and fatigue reduction. Ideal for individuals experiencing high levels of stress, Stress B-Complex provides support for the nervous, immune, and mental systems.
B vitamins play fundamental roles in the body, including converting food into energy, synthesizing neurotransmitters, and maintaining healthy skin, hair, and nails. This supplement also helps protect cells against oxidative damage, promoting overall well-being and vitality.
✅ May help reduce tiredness and fatigue.
✅ Supports energy and mental metabolism.
✅ May help strengthen the immune system during periods of stress.
✅ May improve the body's ability to cope with challenging situations and promotes calmness and mental clarity.
✅ Active forms of vitamins like methylcobalamin (B12) and methylfolate (B9), easily utilized by the body.
Thorne's Stress B-Complex stands out from other B complexes due to its reinforced dose of pantothenic acid (vitamin B5 — 250 mg per capsule), an essential nutrient for the synthesis of coenzyme A — a fundamental cofactor in over 100 metabolic reactions, including the metabolism of fats, proteins, and carbohydrates, and the synthesis of adrenocortical hormones. Vitamins B1 (thiamine HCl), B2 (riboflavin + active R5P), B3 (niacinamide), B6 (pyridoxine HCl + active P5P), folate (5-MTHF/Quatrefolic® from Gnosis S.p.A.), and B12 (methylcobalamin) are present in partially or fully active forms, ready to be used by the body without additional conversion. Folate in the 5-MTHF form and B12 as methylcobalamin are the methylated forms in this formula — relevant for those with MTHFR gene variants that hinder the conversion of conventional forms. Biotin (80 mcg) and choline (choline citrate, 14 mg) complete the formula. The product is not yeast-derived.
Excipients include hydroxypropyl methylcellulose capsule (vegetable cellulose), microcrystalline cellulose, calcium laurate, and silicon dioxide. Lactose-free, palmitate-free, magnesium stearate-free, and vegetable stearate-free.
To consider
- Folate in the 5-MTHF form does not interfere with the anti-inflammatory activity of methotrexate (used in psoriasis and rheumatoid arthritis) — it can be used by people with these conditions under medical supervision. However, 5-MTHF supplementation is not recommended concurrently with methotrexate oncological therapy without the oncologist's guidance.
Vitamin B1 (as thiamine HCl), 50 mg/4545%
Vitamin B2 (as 25 mg riboflavin and 3.6 mg N-riboflavin 5 phosphate), 28.6 mg/2043%
Vitamin B3 (as niacinamide), 80 mg NE/500%
Vitamin B6 (25 mg pyridoxine hydrochloride and 3.4 mg pyridoxal 5 phosphate), 28.4 mg/2029%
Vitamin B12 (methylcobalamin), 100 µg/4000%
Biotin, 80 µg/160%
Folate (5 MTHF Glucosamine), 200 µg/100%
Pantothenic acid (as calcium pantothenate), 250 mg/4167%
Choline (as choline citrate), 14 mg/**
Ingredients:Vitamins, hypromellose capsule (made from cellulose), microcrystalline cellulose (filler), choline citrate, calcium laurate (flow agent), silicon dioxide (anti-caking agent)
1 capsule daily
* NRV — Nutrient Reference Value.
** NRV not established.
💊 Food supplements are not a substitute for a varied and balanced diet or a healthy lifestyle.
🤰 If pregnant or breastfeeding, consult your doctor before taking this supplement.
⚠️ Not recommended in cases of hypersensitivity or allergy to any of the ingredients, or when interactions between another product and any of its constituents have been described.
🕐 Do not exceed the recommended daily dose. Keep out of reach and sight of children.
🌡️ Store in a cool, dry place, away from light.
FAQs
Stress B-Complex is a complete formula with all eight B vitamins in their active forms, with a boosted dose of pantothenic acid (B5). It can contribute to the reduction of tiredness and fatigue, normal energy metabolism, the functioning of the nervous system, and immune balance — especially during periods of increased physical or mental demand.
It can be useful for those dealing with periods of increased professional or physical demands, those experiencing persistent fatigue, mood imbalances or difficulty concentrating, individuals with MTHFR genetic variants affecting B vitamin metabolism, those taking medication that depletes B vitamins (such as metformin, oral contraceptives, or proton pump inhibitors), and those wanting to support adrenal axis balance. Also relevant for people with burnout, chronic fatigue syndrome, anxiety, or stress-related sleep disorders.
The main differentiator is the enhanced dose of pantothenic acid (vitamin B5 — 250 mg, about 4 to 5 times higher than that of a standard B complex), particularly relevant for supporting the adrenal glands and energy metabolism in demanding situations. Vitamins B2, B6, folate, and B12 are also present in partially or fully active forms (R5P, P5P, 5-MTHF, and methylcobalamin).