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5 MTHF 1 Mg 60 Caps Thorne

Price: 33,00€

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Recommended for:
✅ Individuals with difficulty converting standard folate.
✅ Nutritional support for brains requiring balanced neurotransmitters (mood, concentration).
✅ Support for cardiovascular health, red blood cell production, and in regimes where there is an increased need for folate (certain stages of pregnancy, if approved by a professional).
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5 MTHF 1 mg Thorne for daily support with active folate

Thorne's 5-MTHF 1 mg is a folate supplement in its most bioavailable and active form, L-5-methyltetrahydrofolate (5-MTHF). This coenzymated form of folate is quickly absorbed and utilized by the body, being especially useful for people with the MTHFR gene mutation, who have difficulty converting folic acid into its active form.

5-MTHF is essential for various biological processes, including the production of neurotransmitters such as serotonin, dopamine, and epinephrine, which are crucial for brain function and mood regulation. In addition, 5-MTHF is fundamental for cardiovascular health, as it can help maintain normal homocysteine levels, an amino acid that, in excess, can increase cardiovascular risk.

This supplement is also especially important for pregnant women or women planning to conceive, as folate is essential for the healthy development of the fetal brain and spinal cord. With 1 mg of 5-MTHF per capsule, this product offers the ideal dosage to support general health and the function of vital systems.

✅Cardiovascular support: 5-MTHF can help regulate homocysteine levels, contributing to cardiovascular health and reducing the risk of heart disease.

✅ Mental and mood health: Participates in the production of neurotransmitters, such as serotonin and dopamine, and can help control mood and brain function.

✅ Healthy fetal development: 5-MTHF is crucial during pregnancy for the healthy development of the fetal brain and spinal cord.

✅ Immune and blood function: Can support the production of healthy blood cells and the proper functioning of the immune system.

✅ Improved nutrient absorption: As a bioactive form of folate, 5-MTHF is quickly absorbed and utilized by the body, providing effective results.

 

Folic Acid, 1 mg / **

Ingredients:Folate (as 5-Methyltetrahydrofolate), Leucine, Silicon Dioxide, Vegetable Capsule

1 capsule per day

* NRV — Nutrient Reference Value.
** NRV not established.

💊 Food supplements are not a substitute for a varied and balanced diet or a healthy lifestyle.

🤰 If pregnant or breastfeeding, consult your doctor before taking this supplement.

⚠️ Not recommended in cases of hypersensitivity or allergy to any of the ingredients, or when interactions between another product and any of its constituents have been described.

🕐 Do not exceed the recommended daily dose. Keep out of reach and sight of children.

🌡️ Store in a cool, dry place, away from light.

Price: 33,00€
5 MTHF 1 Mg 60 Caps Thorne
33,00€

FAQs

Thorne · Active Folate

5-MTHF 1 mg
L-Methylfolate

The active and bioavailable form of folate — ready to be used by cells, regardless of genetic variations in conversion.

Quatrefolic® Gluten-free Soy-free · Dairy-free NSF Certified
Active vs. inactive form

Why L-Methylfolate?

The folic acid found in most supplements is an inactive form that the body needs to convert before it can be used. This conversion can be limited by common genetic variations — 5-MTHF reaches cells already in its ready-to-use form.

This supplement
5-MTHF (Quatrefolic®)
  • Bioavailable form — ready to use
  • Suitable for MTHFR genetic variations
  • Directly involved in the methylation cycle
  • Potentially higher blood levels
Common alternative
Folic Acid
  • Requires prior enzymatic conversion
  • Reduced efficacy in MTHFR C677T carriers
  • Conversion limited by genetic factors
  • Possible accumulation of unmetabolized acid
~60%
of people may have a genetic variation that affects folate conversion
1mg
of L-5-methylfolate per capsule, in Quatrefolic® form
5mg
higher dose version also available
Areas of action

How 5-MTHF may act in the body

L-methylfolate participates in biochemical pathways that may be relevant to daily well-being.

Neurological well-being

Folate contributes to the normal functioning of the nervous system. 5-MTHF may contribute to neurotransmitter synthesis pathways through the activation of enzymatic cofactors.

Cardiovascular health

Folate contributes to normal homocysteine metabolism. 5-MTHF may also participate in mechanisms supporting vascular elasticity and normal blood flow.

Methylation cycle

5-MTHF participates in the donation of methyl groups, activating the SAMe molecule which may contribute to numerous biochemical pathways — from DNA synthesis to gene regulation.

Periconceptional period

Folic acid and folate contribute to the normal growth of maternal tissue during pregnancy. The active form may be advantageous for women planning to conceive.

Why might folate be lacking?

Five reasons for folate deficiency

Even with a balanced diet, folate levels can be insufficient for reasons identified in scientific literature.

01 Insufficient dietary intake — green leafy vegetables and legumes are the main sources, but cooking can significantly reduce the available content.
02 MTHFR genetic variations — polymorphisms like C677T reduce the ability to convert inactive folate into the form usable by cells.
03 Gastric acid inhibitors — prolonged use of antacids can affect the absorption of various B vitamins, including folate.
04 Certain medications — some drugs can interfere with folate metabolism, reducing its circulating levels.
05 Gastrointestinal conditions — situations affecting the intestinal lining can compromise the absorption of dietary folate.
Suitability

Who may benefit

Those who have identified an MTHFR genetic variant in testing
Women of childbearing age or planning pregnancy
Those seeking additional support for folate metabolism
Those using medication that may interfere with folate (under supervision)